Introduction of Dr. Wan-Xi Yang

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Wan-Xi Yang, Ph.D.
The Principal Investigator of Sperm Laboratory at Zhejiang University
E-mail: wxyang@spermlab.org

The molecular mechanism of acrosome biogenesis and nuclear shaping still remain unknown up to date. I have been working on functions of kinesin related motor proteins during spermatogenesis, especially the molecular mechanism of acrosome formation and nucleus shaping. We have found kinesin related motor protein KIFC1 participates in acrosome formation. I am also very interested in sperm diversity of marine animals, eapecially that of crustaceans and mollusks. My future plan is to do further investigation of functions of different motor proteins (both plus- and minus-ended motor proteins)during mammalian and/or zebra fish spermatogenesis. About the sperm diversity, I will focus on molecular mechanisms of acrosome formation as well as nucleus shaping. Comparative studies of sperm will be made on those of marine crustaceans and mollusks. A potential evolutionary route may be found depends on the molecular mechanism of spermatogenesis.

My projects include both basic research (the one I did in my former visiting lab was a part of NIH grant, "Mitotic Kinesin in Mammalian Spermatogenesis", and a blend of basic and applied research (study on the "Egg-loss mechanisms of Chinese mitten crab", which was granted to me by Zhejiang Natural Science Fundation, China). My students in China are now working on an international co-study project funded by China and Portugal Governments (to me and my Portuguese collaborator). My Portuguese partner is Dr. Antonina dos Santos, a senior scientist from Portugal Marine & Fisheries Institute.

To know my recent projects, please click here...

<< Click here for my Curriculum Vitae>>

    Current address:
      Wan-Xi Yang, Ph.D.
      Associate Professor
      College of Life Sciences
      Zhejiang University
      Zi Jin Gang Campus
      388 Yu Hang Tang   Road,
      Hangzhou,
      Zhejiang    310058
      China

    E-mail:
      wxyang@spermlab.org